AbstractDuring cellular stress it Recycle-Appliance is essential for cells to alter their gene expression to adapt and survive.Gene expression is regulated at multiple levels, but translation regulation is both a method for rapid changes to the proteome and, as one of the most energy-intensive cellular processes, a way to efficiently redirect cellular resources during stress conditions.Despite this ideal positioning, many of the specifics of how translation is regulated, positively or negatively, during various types of cellular Niacin stress remain poorly understood.To further assess this regulation, we examined the essential translation factor Ded1, an RNA helicase that has been previously shown to play important roles in the translational response to cellular stress.In particular, ded1ded1Saccharomyces cerevisiae.